Establishment and validation of a 28-day mortality prediction model based on the lactate dehydrogenase/albumin ratio in patients with severe pneumonia

LAR is an effective biomarker with significant clinical value in predicting 28-day mortality in patients with severe pneumonia. The LAR-based prediction model enhances the accuracy of mortality risk assessment, especially in non-septic patients. Combined with machine learning techniques, LAR offers a novel tool for early clinical risk evaluation and holds promising potential for clinical application.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-01-21
DOI
https://doi.org/10.3389/fmed.2025.1696945
Primary Topic
Sepsis Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Establishment and validation of a 28-day mortality prediction model based on the lactate dehydrogenase/albumin ratio in patients with severe pneumonia

Kai Ma, H. Zhou, Hong Luo
Frontiers in Medicine
Sepsis Diagnosis and Treatment
article

Establishment and validation of a 28-day mortality prediction model based on the lactate dehydrogenase/albumin ratio in patients with severe pneumonia

Kai Ma, H. Zhou, Hong Luo
article en

Abstract

LAR is an effective biomarker with significant clinical value in predicting 28-day mortality in patients with severe pneumonia. The LAR-based prediction model enhances the accuracy of mortality risk assessment, especially in non-septic patients. Combined with machine learning techniques, LAR offers a novel tool for early clinical risk evaluation and holds promising potential for clinical application.

Frontiers in MedicineVol. 12
Central South University (CN), Hunan Provincial Center for Disease Control and Prevention (CN), Second Xiangya Hospital of Central South University (CN)
National Natural Science Foundation of China, National Science and Technology Major Project
Good health and well-being
Openalex Percentile: Top 83%
Sepsis Diagnosis and Treatment
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Establishment and validation of a 28-day mortality prediction model based on the lactate dehydrogenase/albumin ratio in patients with severe pneumonia — Kai Ma, H. Zhou, et al. · Frontiers in Medicine (2026) | TGRS Research Map | TGRS