Clinical-radiologic-pathologic characterization of diabetic mastopathy: an analysis of 21 cases

DMP presents a diagnostic paradox of benign mammographic but suspicious sonographic appearances. The characteristic "absence of space-occupying effect" on ultrasound is a key differentiating feature from breast carcinoma. Recognizing this sign, along with atypical patterns like ductal dilation, can increase pre-biopsy diagnostic suspicion in patients with long-standing diabetes, potentially guiding more conservative management. Histopathological confirmation remains essential.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2026-01-21
DOI
https://doi.org/10.3389/fendo.2026.1691578
Primary Topic
Breast Lesions and Carcinomas
Type
article
Field-Weighted Citation Impact
0.00
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article

Clinical-radiologic-pathologic characterization of diabetic mastopathy: an analysis of 21 cases

Juan Chen, Chao Zhang, Liwei Song, Z. Liu et al.
Frontiers in Endocrinology
Breast Lesions and Carcinomas
article

Clinical-radiologic-pathologic characterization of diabetic mastopathy: an analysis of 21 cases

Juan Chen, Chao Zhang, Liwei Song, Z. Liu, Zhuojun Qi
article en

Abstract

DMP presents a diagnostic paradox of benign mammographic but suspicious sonographic appearances. The characteristic "absence of space-occupying effect" on ultrasound is a key differentiating feature from breast carcinoma. Recognizing this sign, along with atypical patterns like ductal dilation, can increase pre-biopsy diagnostic suspicion in patients with long-standing diabetes, potentially guiding more conservative management. Histopathological confirmation remains essential.

Frontiers in EndocrinologyVol. 17
Shanxi Medical University (CN), Shanxi Provincial Cancer Hospital (CN), First Hospital of Shanxi Medical University (CN), Shanxi Provincial People’s Hospital (CN)
Good health and well-being
Openalex Percentile: Top 83%
Breast Lesions and Carcinomas
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Clinical-radiologic-pathologic characterization of diabetic mastopathy: an analysis of 21 cases — Juan Chen, Chao Zhang, et al. · Frontiers in Endocrinology (2026) | TGRS Research Map | TGRS