Analyses of the Effects of Wild‐Type TDP‐43 Overexpression in Oxytocin Neurons in Mice
Selective TDP-43 overexpression in oxytocin neurons in the paraventricular nucleus of the hypothalamus causes a decrease in oxytocin-immunopositive cells compared to uninjected mice. AAV-mediated TDP-43 overexpression in oxytocin neurons does not appear to be a major driver of behavioural and metabolic phenotypes in mice.
Authors
- Sofia Bergh
- Oskar Simonsson
- Åsa Petersén
Institutions
- Lund University (SE)
- Skåne University Hospital (SE)
Publication Details
- Journal
- Neuropathology and Applied Neurobiology
- Published
- 2026-01-21
- DOI
- https://doi.org/10.1111/nan.70059
- Primary Topic
- Neuroendocrine regulation and behavior
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Knut och Alice Wallenbergs Stiftelse
- Vetenskapsrådet