Toxicity of ivermectin on multiple insecticide-resistant populations of Anopheles gambiae sensu lato, Aedes aegypti, and Culex mosquitoes
The study showed that the multiple insecticide-resistant An. gambiae s.l. population was more tolerant to ivermectin compared with the susceptible strain, but more susceptible to the drug compared with Ae. aegypti. These findings suggest heterogeneity in ivermectin responses across the mosquito species and resistant phenotypes, and therefore, further studies are needed to identify the mechanisms underlying these differences and to assess their relevance under broader epidemiological and ecological contexts.
Authors
- Guenter Froeschl (ORCID: https://orcid.org/0000-0003-2743-7555)
- Godwin Amlalo (ORCID: https://orcid.org/0000-0003-1280-4770)
- Dorothy Obuobi
- Andreas A Kudom (ORCID: https://orcid.org/0000-0002-7577-9368)
- Andreas Wieser
Institutions
- University of Cape Coast (GH)
- University of Ghana (GH)
- LMU Klinikum (DE)
- Noguchi Memorial Institute for Medical Research (GH)
- Fraunhofer Institute for Translational Medicine and Pharmacology (DE)
- German Center for Infection Research (DE)
- Institute of Medical Microbiology and Hygiene (DE)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- Parasites & Vectors
- Published
- 2026-01-21
- DOI
- https://doi.org/10.1186/s13071-025-07227-7
- Primary Topic
- Malaria Research and Control
- Type
- article
- Field-Weighted Citation Impact
- 0.00