Exogenous parathyroid hormone (1–34) attenuates knee osteoarthritis in mice through activating the TGF-β/Smad signaling pathway
PTH (1-34) attentuates knee OA induced by ACLT by stimulating proliferation, inhibiting hypertrophy and maturation of chondrocytes and the degradation of articular cartilage, and activating the TGF-β/Smad signaling pathway.
Authors
- Haonan Qin (ORCID: https://orcid.org/0000-0002-1272-858X)
- Huan Liu (ORCID: https://orcid.org/0000-0001-5604-9047)
- Yunru GE
- Qirui Ding
- Shouguo Wang
- Haoran Jin
- Peng Sun
Institutions
- Xuzhou Medical College (CN)
- Huaian First People’s Hospital (CN)
- Second People’s Hospital of Huai’an (CN)
- Huaiyin Normal University (CN)
- Huaiyin Institute of Technology (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- HORMONES
- Published
- 2026-01-21
- DOI
- https://doi.org/10.1007/s42000-025-00749-w
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00