IgG4-related prostatitis: expanding the spectrum of IgG4-related disease. A systematic review

IgG4-related prostatitis is a rare and likely under-recognised manifestation of IgG4-RD. Its overlap with benign and malignant prostatic disorders delays diagnosis. Serum IgG4 and PSA are unreliable markers of disease and monitoring. Glucocorticoids remain first-line therapy, with surgery in obstructive cases. Multicentre studies are needed to define prevalence, natural history, and optimal management.

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Publication Details

Journal
Clinical and Experimental Rheumatology
Published
2025-10-16
DOI
https://doi.org/10.55563/clinexprheumatol/i8eh4g
Primary Topic
IgG4-Related and Inflammatory Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

IgG4-related prostatitis: expanding the spectrum of IgG4-related disease. A systematic review

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Clinical and Experimental Rheumatology
IgG4-Related and Inflammatory Diseases
article

IgG4-related prostatitis: expanding the spectrum of IgG4-related disease. A systematic review

Cristina Pamfil, R. Talarico, Georgiana Cabău, Teodor Nicolae Onea, Camelia Bucsa, Maia Ioana Mihon, Ioana Felea, Victor Surdu, Laura Damian
article en

Abstract

IgG4-related prostatitis is a rare and likely under-recognised manifestation of IgG4-RD. Its overlap with benign and malignant prostatic disorders delays diagnosis. Serum IgG4 and PSA are unreliable markers of disease and monitoring. Glucocorticoids remain first-line therapy, with surgery in obstructive cases. Multicentre studies are needed to define prevalence, natural history, and optimal management.

Clinical and Experimental Rheumatology
Iuliu Hațieganu University of Medicine and Pharmacy (RO), Azienda Ospedaliera Universitaria Pisana (IT)
Good health and well-being
Openalex Percentile: Top 25%
IgG4-Related and Inflammatory Diseases
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