Iodometry: A straightforward “tank side-test” to determine formaldehyde concentrations in anatomical tanks

In anatomical preservation, low formaldehyde concentrations are recommended because of the carcinogenic potential of formaldehyde. However, in big basins with a varying number of bodies inside it may be difficult to estimate the formaldehyde concentration. Here, a feasible titration method, i.e. iodometry, was described to measure formaldehyde concentrations in anatomical preservation tanks. This method was compared to head-space mass spectrometry-. Results of triplet measurements of the iodometry were coherent and fitted to nominal formaldehyde concentrations. The formaldehyde concentrations in the preservation tanks were found to be in the anticipated ranges between 2 % and 4 %. Therefore, an estimation of the formaldehyde concentration in preservation tanks is possible using the described quick and cost-effective method.

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Publication Details

Journal
Annals of Anatomy - Anatomischer Anzeiger
Published
2026-01-21
DOI
https://doi.org/10.1016/j.aanat.2026.152794
Primary Topic
Anatomy and Medical Technology
Type
article
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article

Iodometry: A straightforward “tank side-test” to determine formaldehyde concentrations in anatomical tanks

Thomas Tschernig, Armin Weber, Markus R. Meyer, Stefan Wagenpfeil et al.
Annals of Anatomy - Anatomischer Anzeiger
Anatomy and Medical Technology
article

Iodometry: A straightforward “tank side-test” to determine formaldehyde concentrations in anatomical tanks

Thomas Tschernig, Armin Weber, Markus R. Meyer, Stefan Wagenpfeil, Carola Meier, Anne-Marie Schmidt, Michael Kohr, Carla L. Janko
article en

Abstract

In anatomical preservation, low formaldehyde concentrations are recommended because of the carcinogenic potential of formaldehyde. However, in big basins with a varying number of bodies inside it may be difficult to estimate the formaldehyde concentration. Here, a feasible titration method, i.e. iodometry, was described to measure formaldehyde concentrations in anatomical preservation tanks. This method was compared to head-space mass spectrometry-. Results of triplet measurements of the iodometry were coherent and fitted to nominal formaldehyde concentrations. The formaldehyde concentrations in the preservation tanks were found to be in the anticipated ranges between 2 % and 4 %. Therefore, an estimation of the formaldehyde concentration in preservation tanks is possible using the described quick and cost-effective method.

Annals of Anatomy - Anatomischer AnzeigerVol. 265
Institute of Pathology Celle (DE), Thomas University (US), Saarland University (DE)
Life in Land
Openalex Percentile: Top 83%
Anatomy and Medical Technology
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