Myocardial fibrosis and strain impairment in treatment-naïve cancer patients: insights into cancer-related myocardial remodeling from a prospective case–control CMR study

Treatment-naive cancer patients exhibit subclinical myocardial alterations, characterized by elevated native T1 and reduced global longitudinal strain. Cardiac magnetic resonance emerges as a valuable tool for identifying early biomarkers of myocardial dysfunction, offering opportunities for risk stratification and proactive management in cardio-oncology.

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Publication Details

Journal
La radiologia medica
Published
2026-01-21
DOI
https://doi.org/10.1007/s11547-026-02178-0
Primary Topic
Chemotherapy-induced cardiotoxicity and mitigation
Type
article
Field-Weighted Citation Impact
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article

Myocardial fibrosis and strain impairment in treatment-naïve cancer patients: insights into cancer-related myocardial remodeling from a prospective case–control CMR study

R. Mazza, Lorenzo Monti, Carmelo Carlo-Stella, Stefano Figliozzi et al.
La radiologia medica
Chemotherapy-induced cardiotoxicity and mitigation
article

Myocardial fibrosis and strain impairment in treatment-naïve cancer patients: insights into cancer-related myocardial remodeling from a prospective case–control CMR study

R. Mazza, Lorenzo Monti, Carmelo Carlo-Stella, Stefano Figliozzi, Federica Catapano, Gianluigi Condorelli, Riccardo Levi, Marco Francone, Giulio Stefanini, Costanza Lisi
article en

Abstract

Treatment-naive cancer patients exhibit subclinical myocardial alterations, characterized by elevated native T1 and reduced global longitudinal strain. Cardiac magnetic resonance emerges as a valuable tool for identifying early biomarkers of myocardial dysfunction, offering opportunities for risk stratification and proactive management in cardio-oncology.

La radiologia medica
Humanitas University (IT), Istituti Clinici Scientifici Maugeri (IT), IRCCS Humanitas Research Hospital (IT)
Good health and well-being
Openalex Percentile: Top 84%
Chemotherapy-induced cardiotoxicity and mitigation
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