Sarcopenia in type 2 diabetes mellitus: an imaging review

Sarcopenia is characterized by an age-related decline in muscle mass, strength, or endurance. It is increasingly prevalent in patients with type 2 diabetes mellitus (T2DM) and is now regarded as a key complication of the disease. Additionally, it has a significant impact on patients' prognosis. Imaging methods are crucial tools for assessing muscle mass and microchanges. Moreover, they can facilitate the early diagnosis of sarcopenia. Thus, this article reviews the pathological basis and clinical manifestations of sarcopenia in T2DM, the advantages and disadvantages of imaging assessment methods, their specific applications, imaging manifestations, and research progress.

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Journal
Frontiers in Medicine
Published
2026-01-21
DOI
https://doi.org/10.3389/fmed.2026.1637499
Primary Topic
Nutrition and Health in Aging
Type
article
Field-Weighted Citation Impact
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article

Sarcopenia in type 2 diabetes mellitus: an imaging review

Heng Zhao, Hao Lei, Qiqun Zeng, Jincai Liu et al.
Frontiers in Medicine
Nutrition and Health in Aging
article

Sarcopenia in type 2 diabetes mellitus: an imaging review

Heng Zhao, Hao Lei, Qiqun Zeng, Jincai Liu, Zhang Li, Guanghua Luo, Yusheng Li, Hongtao Jiang, Lei He, Jingjun Zhu, Wenbin Gu
article en

Abstract

Sarcopenia is characterized by an age-related decline in muscle mass, strength, or endurance. It is increasingly prevalent in patients with type 2 diabetes mellitus (T2DM) and is now regarded as a key complication of the disease. Additionally, it has a significant impact on patients' prognosis. Imaging methods are crucial tools for assessing muscle mass and microchanges. Moreover, they can facilitate the early diagnosis of sarcopenia. Thus, this article reviews the pathological basis and clinical manifestations of sarcopenia in T2DM, the advantages and disadvantages of imaging assessment methods, their specific applications, imaging manifestations, and research progress.

Frontiers in MedicineVol. 13
First Affiliated Hospital of Henan University of Science and Technology (CN), The Central Hospital of Shaoyang (CN), First Affiliated Hospital of University of South China (CN), University of South China (CN)
Good health and well-being
Openalex Percentile: Top 84%
Nutrition and Health in Aging
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