Modeled Health and Economic Burden of Frailty and Falls Among Adults With HIV

In this decision analytic modeling study of frailty and falls among people with HIV and viral suppression, the lifetime QALYs lost and costs attributable to frailty and falls were substantial. These findings highlight the potential clinical and economic benefits that could result from interventions to identify, prevent, and treat frailty and falls among people with HIV.

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Publication Details

Journal
JAMA Network Open
Published
2026-01-21
DOI
https://doi.org/10.1001/jamanetworkopen.2025.54809
Primary Topic
HIV-related health complications and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Modeled Health and Economic Burden of Frailty and Falls Among Adults With HIV

E. Losina, Reyhaneh Zafarnejad, Emily P. Hyle, Karen C. Smith et al.
JAMA Network Open
HIV-related health complications and treatments
article

Modeled Health and Economic Burden of Frailty and Falls Among Adults With HIV

E. Losina, Reyhaneh Zafarnejad, Emily P. Hyle, Karen C. Smith, Todd T. Brown, Kenneth A. Freedberg, Kristine M. Erlandson, Cathryn Brown
article en

Abstract

In this decision analytic modeling study of frailty and falls among people with HIV and viral suppression, the lifetime QALYs lost and costs attributable to frailty and falls were substantial. These findings highlight the potential clinical and economic benefits that could result from interventions to identify, prevent, and treat frailty and falls among people with HIV.

JAMA Network OpenVol. 9(1)
Brigham and Women's Hospital (US), Harvard University (US), Johns Hopkins University (US), Johns Hopkins Medicine (US), Massachusetts General Hospital (US), University of Colorado Anschutz Medical Campus (US)
Good health and well-being
Openalex Percentile: Top 85%
HIV-related health complications and treatments
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