Magnetic resonance imaging-based adenohypophyseal volume for diagnosing hypothalamic-pituitary-gonadal axis activation in pre- and at-puberty children
aPV may have significant potential to be a noninvasive diagnostic biomarker for assessing HPG axis activation in children with CPP. The developed regression models, incorporating aPV, age, and weight, provide promising diagnostic performance and may potentially reduce the reliance on invasive GnRH stimulation tests.
Authors
- Qiuxia Wang (ORCID: https://orcid.org/0000-0001-6536-2131)
- Wangyu Liu (ORCID: https://orcid.org/0009-0007-0128-4067)
- Xianrong Kong
- Sikang Gao (ORCID: https://orcid.org/0000-0002-4570-5026)
- Guojun Ding (ORCID: https://orcid.org/0000-0002-7485-9171)
- Jianjian Cai
- Longbiao Cai
- Dong Liu
- Tian Tian
- Jicheng Fang
- Yunyun Zhao
- Qin Liu
Institutions
- Bayer (United States) (US)
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Quantitative Imaging in Medicine and Surgery
- Published
- 2026-01-21
- DOI
- https://doi.org/10.21037/qims-2025-1677
- Primary Topic
- Hypothalamic control of reproductive hormones
- Type
- article
- Field-Weighted Citation Impact
- 0.00