IgG Fc binding protein (FCGBP) inhibits the development of laryngeal squamous cell carcinoma and cisplatin resistance through the PIGR/JAK2/STAT3 pathway
These findings suggest that the FCGBP/PIGR/JAK2/STAT3 axis regulates CDDP resistance in LSCC and that FCGBP may serve as a potential therapeutic target to improve cisplatin efficacy in treating LSCC.
Authors
- Yunlan Zeng
- Ming Xiong (ORCID: https://orcid.org/0009-0006-2180-5889)
- Xuemei Wan
- Yundan Bai
- Lin Chen
Institutions
- Affiliated Hospital of Southwest Medical University (CN)
- Integrated Chinese Medicine (China) (HK)
- Second Affiliated Hospital of Chengdu University of Traditional Chinese (CN)
Publication Details
- Journal
- Radiology and Oncology
- Published
- 2026-01-21
- DOI
- https://doi.org/10.2478/raon-2026-0003
- Primary Topic
- Monoclonal and Polyclonal Antibodies Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Sichuan Province