Expert consensus on the diagnosis and management of tooth developmental anomalies
Tooth developmental anomalies are a group of disorders caused by unfavorable factors affecting the tooth development process, resulting in abnormalities in tooth number, structure, and morphology. These anomalies typically manifest during childhood, impairing dental function, maxillofacial development, and facial aesthetics, while also potentially impacting overall physical and mental health. The complex etiology and diverse clinical phenotypes of these anomalies pose significant challenges for prevention, early diagnosis, and treatment. As they usually emerge early in life, long-term management and multidisciplinary collaboration in dental care are essential. However, there is currently a lack of systematic clinical guidelines for the diagnosis and treatment of these conditions, adding to the difficulties in clinical practice. In response to this need, this expert consensus summarizes the classifications, etiology, typical clinical manifestations, and diagnostic criteria of tooth developmental anomalies based on current clinical evidence. It also provides prevention strategies and stage-specific clinical management recommendations to guide clinicians in diagnosis and treatment, promoting early intervention and standardized care for these anomalies.
Authors
- Shuguo Zheng (ORCID: https://orcid.org/0000-0001-6717-5196)
- Zhuan Bian
- Yuegui Jiang (ORCID: https://orcid.org/0000-0002-4018-2211)
- Jingxian Zhu (ORCID: https://orcid.org/0000-0003-0095-654X)
- D. Chen
- Yanli Zhang (ORCID: https://orcid.org/0000-0002-2497-1165)
- Jiewen Dai
- Yanghe Pan (ORCID: https://orcid.org/0009-0008-1485-058X)
- T T Zhang
- Liwei Zheng
- Zhenjin Zhao
- Yao Sun
- Mian Wan (ORCID: https://orcid.org/0000-0002-3373-2836)
- Yihuai Pan
- Baoshan Xu
- D Han
- Cui Huang
- Zhipeng Fan
- Zhonglin Jia
- Wenmei Wang
- Qinglin Zhu
- Miao He
- Tiemei Wang
- Wei Yin
Institutions
- Tongji University (CN)
- Capital Medical University (CN)
- Peking University (CN)
- Sichuan University (CN)
- Wenzhou Medical University (CN)
- Wuhan University (CN)
- National Clinical Research Center for Digestive Diseases (CN)
- Shanghai Stomatological Hospital (CN)
- Shanghai Ninth People's Hospital (CN)
- National Clinical Research (US)
- Stomatology Hospital (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
- State Key Laboratory of Oral Diseases
- Tianjin Medical University (CN)
- Nanjing Medical University (CN)
- Xi'an Jiaotong University (CN)
- Nanjing University (CN)
- China Medical University (CN)
- Air Force Medical University (CN)
Publication Details
- Journal
- International Journal of Oral Science
- Published
- 2026-01-20
- DOI
- https://doi.org/10.1038/s41368-025-00401-8
- Primary Topic
- dental development and anomalies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Fundamental Research Funds for the Central Universities