Altered white matter connectivity is linked to language abilities in children with autism spectrum disorder: An automated fiber quantification study

Our findings underscore the importance of white matter lateralization and microstructural integrity in supporting language abilities in young children with ASD. The study provides novel insights into the neuroanatomical foundations of language deficits and their association with symptom severity, highlighting the value of point-wise analyses in understanding ASD-related connectivity alterations.

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Publication Details

Journal
Frontiers in Psychiatry
Published
2026-01-20
DOI
https://doi.org/10.3389/fpsyt.2025.1731647
Primary Topic
Autism Spectrum Disorder Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Altered white matter connectivity is linked to language abilities in children with autism spectrum disorder: An automated fiber quantification study

Shuiqun Zhang, Qingshan HUANG, Kaiyu Huang, Yaqiong Xiao et al.
Frontiers in Psychiatry
Autism Spectrum Disorder Research
article

Altered white matter connectivity is linked to language abilities in children with autism spectrum disorder: An automated fiber quantification study

Shuiqun Zhang, Qingshan HUANG, Kaiyu Huang, Yaqiong Xiao, Aiwen Yi, Yubin Hu
article en

Abstract

Our findings underscore the importance of white matter lateralization and microstructural integrity in supporting language abilities in young children with ASD. The study provides novel insights into the neuroanatomical foundations of language deficits and their association with symptom severity, highlighting the value of point-wise analyses in understanding ASD-related connectivity alterations.

Frontiers in PsychiatryVol. 16
Guangzhou University of Chinese Medicine (CN), King's College London (GB), Society for Maternal-Fetal Medicine (US), Third Affiliated Hospital of Guangzhou Medical University (CN), Key Laboratory of Guangdong Province (CN), Guangdong Province Women and Children Hospital (CN), Shenzhen University Health Science Center (CN), Guangzhou Medical University (CN)
National Natural Science Foundation of China
Quality Education
Openalex Percentile: Top 83%
Autism Spectrum Disorder Research
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