Single-center experience with immune checkpoint inhibitor-related ureteritis and cystitis
This pioneering cohort study provides the first systematic investigation of ICI-UC, establishing its incidence and comprehensively characterizing clinical and imaging features. Through cohort analysis, we propose a novel severity grading system with corresponding treatment algorithms, while additionally exploring the therapeutic potential of JAK inhibitors for steroid-dependent cases.
Authors
- Muwen Nie (ORCID: https://orcid.org/0009-0009-4992-0303)
- Chenyu Wang (ORCID: https://orcid.org/0000-0001-7135-7662)
- Na Zhou (ORCID: https://orcid.org/0000-0001-5768-8676)
- Hongyan YING
- C. Bai
- Yuan Liu
- Wei Qiu
- Lin Zhao
- Xiang Wang
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-01-20
- DOI
- https://doi.org/10.3389/fimmu.2025.1727822
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Peking Union Medical College Hospital