Correlation between systemic inflammation markers and insulin resistance in type 2 diabetes mellitus patients and its diagnostic value analysis

Systemic inflammatory markers, particularly NLR, are significantly associated with insulin resistance in patients with T2DM. Although the discriminative performance of NLR was modest, its simplicity, low cost, and availability from routine complete blood counts support its potential role as a complementary marker associated with IR rather than a standalone diagnostic tool. Prospective studies are needed to clarify temporal relationships and validate these findings across diverse populations.

Authors

Institutions

Publication Details

Journal
Frontiers in Medicine
Published
2026-01-20
DOI
https://doi.org/10.3389/fmed.2025.1737989
Primary Topic
Adipokines, Inflammation, and Metabolic Diseases
Type
article
Field-Weighted Citation Impact
0.00

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Correlation between systemic inflammation markers and insulin resistance in type 2 diabetes mellitus patients and its diagnostic value analysis

Meiping Yan, Lei He, Dapeng Mo, Hang Li et al.
Frontiers in Medicine
Adipokines, Inflammation, and Metabolic Diseases
article

Correlation between systemic inflammation markers and insulin resistance in type 2 diabetes mellitus patients and its diagnostic value analysis

Meiping Yan, Lei He, Dapeng Mo, Hang Li, Youhua Jiang, Xinjing Chen, Zhijing Liang
article en

Abstract

Systemic inflammatory markers, particularly NLR, are significantly associated with insulin resistance in patients with T2DM. Although the discriminative performance of NLR was modest, its simplicity, low cost, and availability from routine complete blood counts support its potential role as a complementary marker associated with IR rather than a standalone diagnostic tool. Prospective studies are needed to clarify temporal relationships and validate these findings across diverse populations.

Frontiers in MedicineVol. 12
Zhujiang Hospital (CN), Southern Medical University (CN)
Southern Medical University
Reduced inequalities
Openalex Percentile: Top 83%
Adipokines, Inflammation, and Metabolic Diseases
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.