Correlation between systemic inflammation markers and insulin resistance in type 2 diabetes mellitus patients and its diagnostic value analysis
Systemic inflammatory markers, particularly NLR, are significantly associated with insulin resistance in patients with T2DM. Although the discriminative performance of NLR was modest, its simplicity, low cost, and availability from routine complete blood counts support its potential role as a complementary marker associated with IR rather than a standalone diagnostic tool. Prospective studies are needed to clarify temporal relationships and validate these findings across diverse populations.
Authors
- Meiping Yan (ORCID: https://orcid.org/0000-0002-6851-082X)
- Lei He (ORCID: https://orcid.org/0000-0002-1019-182X)
- Dapeng Mo (ORCID: https://orcid.org/0000-0001-6641-5573)
- Hang Li (ORCID: https://orcid.org/0000-0002-0011-8880)
- Youhua Jiang (ORCID: https://orcid.org/0000-0003-2735-1399)
- Xinjing Chen
- Zhijing Liang
Institutions
- Zhujiang Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2026-01-20
- DOI
- https://doi.org/10.3389/fmed.2025.1737989
- Primary Topic
- Adipokines, Inflammation, and Metabolic Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Southern Medical University