Rapidly Expanded EBV-Specific T Cells for the Treatment of Refractory EBV Reactivation and EBV-Related Lymphoproliferative Disorders

These results strengthen previously published results using VSTs from healthy donors and further support the development of EBV-specific T cell therapies to treat refractory EBV reactivation and EBV-associated malignancies, particularly in transplant recipients.

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Publication Details

Journal
Open Forum Infectious Diseases
Published
2025-12-26
DOI
https://doi.org/10.1093/ofid/ofag006
Primary Topic
Viral-associated cancers and disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Rapidly Expanded EBV-Specific T Cells for the Treatment of Refractory EBV Reactivation and EBV-Related Lymphoproliferative Disorders

Isabelle Fleury, Camille Tremblay‐Laganière, Stéphanie Thiant, G. Sauvageau et al.
Open Forum Infectious Diseases
Viral-associated cancers and disorders
article

Rapidly Expanded EBV-Specific T Cells for the Treatment of Refractory EBV Reactivation and EBV-Related Lymphoproliferative Disorders

Isabelle Fleury, Camille Tremblay‐Laganière, Stéphanie Thiant, G. Sauvageau, Olivier Veilleux, Imran Ahmad, Caroline Lamarche, P. Teira, Lynne Senécal, Cynthia Thérien, Suzon Collette, Nadia M. Bambace, Cédric Carli, Lorne Schweitzer, Simon F. Dufresne, Julie Orio, Julien Patenaude, Michel Duval, Léa Bernard, Martin Giroux, Thomas Kiss, Denis-Claude Roy, Gabrielle Boudreau, Sylvie Lachance, Jean Roy, Lambert Busque, Sandra Cohen, Jean-Sébastien Delisle, Henrique Bittencourt
article en

Abstract

These results strengthen previously published results using VSTs from healthy donors and further support the development of EBV-specific T cell therapies to treat refractory EBV reactivation and EBV-associated malignancies, particularly in transplant recipients.

Open Forum Infectious DiseasesVol. 13(1)
McGill University Health Centre (CA), Centre Hospitalier Universitaire Sainte-Justine (CA), Hôpital Maisonneuve-Rosemont (CA), Université de Montréal (CA)
Good health and well-being
Openalex Percentile: Top 28%
Viral-associated cancers and disorders
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