Does the urinary microbiome reflect the bladder-cancer-associated microbiome? Characterizing the microbiome in urine and cancer tissue in bladder cancer
In this cohort, bladder-cancer tissue associated microbiome exhibited a distinct microbial signature when compared to urine. These results suggest that the urinary microbiome may not provide an accurate representation of the bladder-cancer associated microbiome. Validation in larger, standardized cohorts with contamination control is warranted.
Authors
- Khurshid A. Guru (ORCID: https://orcid.org/0000-0002-4551-4676)
- Tariq A. Bhat (ORCID: https://orcid.org/0000-0003-0738-8776)
- Justine J. Jacobi (ORCID: https://orcid.org/0000-0002-9109-3294)
- Zhe Jing
- Yakov Klugman
- Prashant K. Singh
- Gary Smith
- Ahmed A. Hussein
- Jianmin Wang
- Jordan Carlson
- David Goodrich
Institutions
- Roswell Park Comprehensive Cancer Center (US)
Publication Details
- Journal
- Urologic Oncology Seminars and Original Investigations
- Published
- 2026-01-20
- DOI
- https://doi.org/10.1016/j.urolonc.2025.12.014
- Citations
- 1
- Primary Topic
- Urinary Tract Infections Management
- Type
- article
- Field-Weighted Citation Impact
- 31.52