Retrospective comparison of the clinical effects of oral semaglutide and <scp>SGLT2</scp> inhibitors treatment in patients with type 2 diabetes
While both drugs elicited comparable effects on glycemic management and body weight reduction in patients with type 2 diabetes, caution is needed when using SGLT2is in patients at potential risk for sarcopenia, as they may lead to less favorable changes in skeletal muscle mass compared to oral semaglutide.
Authors
- Hitoshi Kuwata (ORCID: https://orcid.org/0009-0000-5498-3282)
- Yutaka Seino
- Yasuhiro Omori
- Yuichiro Yamada
- Yuji Yamazaki
- Yoshiyuki Hamamoto
- Ryota Usui
Institutions
- Kansai Electric Power (Japan) (JP)
- Kansai Electric Power Hospital (JP)
Publication Details
- Journal
- Journal of Diabetes Investigation
- Published
- 2026-01-20
- DOI
- https://doi.org/10.1111/jdi.70240
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00