Platelet-to-lymphocyte ratio as a predictor of preoperative venous thrombosis in femoral fracture patients: a retrospective cohort study

PLR is an independent risk factor for lower extremity DVT in patients with femoral fracture, with a modest predictive performance (AUC = 0.60) that slightly outperforms age and NLR in this cohort. While these findings suggest PLR may have potential as a supplementary biomarker for DVT risk stratification, its clinical utility requires further validation in larger, multicenter studies.

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Publication Details

Journal
Frontiers in Cardiovascular Medicine
Published
2026-01-20
DOI
https://doi.org/10.3389/fcvm.2025.1672545
Primary Topic
Venous Thromboembolism Diagnosis and Management
Type
article
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article

Platelet-to-lymphocyte ratio as a predictor of preoperative venous thrombosis in femoral fracture patients: a retrospective cohort study

Jianguang Sun, Dong Li, Kunlun Li
Frontiers in Cardiovascular Medicine
Venous Thromboembolism Diagnosis and Management
article

Platelet-to-lymphocyte ratio as a predictor of preoperative venous thrombosis in femoral fracture patients: a retrospective cohort study

Jianguang Sun, Dong Li, Kunlun Li
article en

Abstract

PLR is an independent risk factor for lower extremity DVT in patients with femoral fracture, with a modest predictive performance (AUC = 0.60) that slightly outperforms age and NLR in this cohort. While these findings suggest PLR may have potential as a supplementary biomarker for DVT risk stratification, its clinical utility requires further validation in larger, multicenter studies.

Frontiers in Cardiovascular MedicineVol. 12
Meizhou City People's Hospital (CN)
Good health and well-being
Openalex Percentile: Top 84%
Venous Thromboembolism Diagnosis and Management
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