A case of primary angiomatoid fibrous histiocytoma in the lung
We encountered a rare case of AFH arising from the left upper pulmonary lobe. Its diagnosis required a combination of histopathological examination, immunohistochemistry, and FISH. ALK protein expression is commonly observed in AFH; however, the underlying mechanism remains unclear, as it does not appear to result from ALK rearrangement or amplification.
Authors
- Yong Wang (ORCID: https://orcid.org/0000-0002-7405-2888)
- Xiaoyu Long
- Chao Liu
Institutions
- Guangdong Academy of Medical Sciences (CN)
- Guangzhou Eighth People's Hospital (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2026-01-20
- DOI
- https://doi.org/10.1007/s12672-026-04461-y
- Primary Topic
- Sarcoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00