Empty lipid nanoparticles (eLNPs) with adjuvant activity induce potent immune responses

These results highlight the ability of empty lipid nanoparticles (eLNPs) to significantly enhance both humoral and cellular immune responses and their potential for clinical translation. This suggests that eLNP hold promise as a novel adjuvant for future vaccine development.

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Publication Details

Journal
British Journal of Pharmacology
Published
2026-01-19
DOI
https://doi.org/10.1111/bph.70340
Primary Topic
Immunotherapy and Immune Responses
Type
article
Field-Weighted Citation Impact
0.00
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article

Empty lipid nanoparticles (eLNPs) with adjuvant activity induce potent immune responses

Yi Wang, Quan Yuan, Jiaxiang Zhang, Si‐Ping Yan et al.
British Journal of Pharmacology
Immunotherapy and Immune Responses
article

Empty lipid nanoparticles (eLNPs) with adjuvant activity induce potent immune responses

Yi Wang, Quan Yuan, Jiaxiang Zhang, Si‐Ping Yan, Man Yang, Y Yun-Chung Wu, Tian‐Ying Zhang, De‐Kui Qiu, Shu‐Yu Wu, Hua‐Long Xiong, Rui‐Tong Chen, Mei‐Feng Nie, Yue Liu, Ruo‐Yao Qi
article en

Abstract

These results highlight the ability of empty lipid nanoparticles (eLNPs) to significantly enhance both humoral and cellular immune responses and their potential for clinical translation. This suggests that eLNP hold promise as a novel adjuvant for future vaccine development.

British Journal of Pharmacology
Xiamen University (CN)
Openalex Percentile: Top 83%
Immunotherapy and Immune Responses
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