Pulmonary Obstruction and Age, Not Activity, Associate With Muscle Oxidative Impairment in Smokers With and Without COPD

Physical activity or radiographic COPD manifestations were not significantly associated with muscle oxidative impairment. Across never smokers and ever smokers with and without COPD, locomotor muscle oxidative capacity was positively associated with FEV<sub>1</sub>%predicted and negatively associated with age.

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Publication Details

Journal
Journal of Cachexia Sarcopenia and Muscle
Published
2026-01-19
DOI
https://doi.org/10.1002/jcsm.70178
Primary Topic
Chronic Obstructive Pulmonary Disease (COPD) Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Pulmonary Obstruction and Age, Not Activity, Associate With Muscle Oxidative Impairment in Smokers With and Without COPD

Fenhai Duan, Harry B. Rossiter, Robert Calmelat, Richard Casaburi et al.
Journal of Cachexia Sarcopenia and Muscle
Chronic Obstructive Pulmonary Disease (COPD) Research
article

Pulmonary Obstruction and Age, Not Activity, Associate With Muscle Oxidative Impairment in Smokers With and Without COPD

Fenhai Duan, Harry B. Rossiter, Robert Calmelat, Richard Casaburi, Alessandra Adami
article en

Abstract

Physical activity or radiographic COPD manifestations were not significantly associated with muscle oxidative impairment. Across never smokers and ever smokers with and without COPD, locomotor muscle oxidative capacity was positively associated with FEV<sub>1</sub>%predicted and negatively associated with age.

Journal of Cachexia Sarcopenia and MuscleVol. 17(1)
Rhode Island Department of Health (US), University of Rhode Island (US), Brown University (US), UCLA Medical Center (US), Harbor–UCLA Medical Center (US)
Good health and well-being
Openalex Percentile: Top 84%
Chronic Obstructive Pulmonary Disease (COPD) Research
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