Co-Existence of Sinonasal Inverted Papilloma and Angiofibroma

Inverted papilloma (IP) and angiofibroma are both rare benign sinonasal tumors that require differentiation, and their coexistence is even rarer. Here, we report an unusual case involving the coexistence of IP and angiofibroma in the nasal cavity. A 77-year-old female who presented with a right-sided nasal mass underwent facial CT, MRI, and punch biopsy of the right nasal mass. Discrepancies were noted between these examinations: a 4 cm enhancing mass displaying features suggestive of angiofibroma on facial CT and MRI, and a benign hyperplastic squamous epithelium indicating IP on biopsy. Preoperative angiography and embolization of the feeding artery of the nasal cavity mass were performed, and endoscopic sinus surgery was performed to remove the tumor. The final pathological results revealed the coexistence of IP and angiofibroma. We emphasize the need for accurate diagnosis and surgical treatment, considering that IP and angiofibroma in the nasal cavity can exist simultaneously.