Comparative In Vitro Assessment of Marginal Microleakage and Caries-Like Lesions Around Common Restorative Materials

Background: Secondary caries formation is still one of the main reasons of restorations fail, mostly caused by the material's resistance to microleakage and marginal sealing ability. The objective of this research was to assess compare the degree of secondary caries development next to restorations made of Glass Ionomer Cement (GIC), Composite Resin, and Amalgam. Methods: The in-vitro study was conducted (March 2024 to August 2024) at Dentistry department at with randomly selected groups (n = 30 each) created from 90 extracted human premolars: Group A (Composite Resin), Group B (Amalgam), and Group C (GIC). In accordance with the guidelines provided by the manufacturers, standardized Class I and II cavities were prepared and restored. The samples were subjected to artificial demineralization (pH cycling) and thermocycling in order to replicate oral conditions that are favorable for the development of marginal caries. In SPSS version 26.0, one-way ANOVA and chi-square tests were used to analyze the data(p < 0.05 as significant). Results: The findings showed that Amalgam restorations had the most severe lesions and the highest leakage (0.87 ± 0.21 mm), while Composite Resin restorations had the lowest microleakage (0.58 ± 0.16 mm) and the lowest caries incidence. GIC exhibited results that were in between (0.72 ± 0.19). The groups differed significantly (p = 0.01 for caries severity and p = 0.002 for leakage). Conclusion: In comparison to Amalgam and GIC, Composite Resin demonstrated better marginal adaptation and resistance to secondary caries. These results highlight the significance of choosing restorative materials to reduce restoration failures.

Authors

Institutions

Publication Details

Journal
Pakistan Journal of Medicine and Dentistry
Published
2026-01-14
DOI
https://doi.org/10.36283/ziun-pjmd15-1/016
Primary Topic
Dental materials and restorations
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Comparative In Vitro Assessment of Marginal Microleakage and Caries-Like Lesions Around Common Restorative Materials

Amjad Hussain, Alvina Ali Shaikh, Muhammad Moazzam, Saeeda O. Ahmed et al.
Pakistan Journal of Medicine and Dentistry
Dental materials and restorations
article

Comparative In Vitro Assessment of Marginal Microleakage and Caries-Like Lesions Around Common Restorative Materials

Amjad Hussain, Alvina Ali Shaikh, Muhammad Moazzam, Saeeda O. Ahmed, Mubashir Rasheed, Ayesha Zafar, Ali Memon Khan, Irum Naz
article en

Abstract

Background: Secondary caries formation is still one of the main reasons of restorations fail, mostly caused by the material's resistance to microleakage and marginal sealing ability. The objective of this research was to assess compare the degree of secondary caries development next to restorations made of Glass Ionomer Cement (GIC), Composite Resin, and Amalgam. Methods: The in-vitro study was conducted (March 2024 to August 2024) at Dentistry department at with randomly selected groups (n = 30 each) created from 90 extracted human premolars: Group A (Composite Resin), Group B (Amalgam), and Group C (GIC). In accordance with the guidelines provided by the manufacturers, standardized Class I and II cavities were prepared and restored. The samples were subjected to artificial demineralization (pH cycling) and thermocycling in order to replicate oral conditions that are favorable for the development of marginal caries. In SPSS version 26.0, one-way ANOVA and chi-square tests were used to analyze the data(p < 0.05 as significant). Results: The findings showed that Amalgam restorations had the most severe lesions and the highest leakage (0.87 ± 0.21 mm), while Composite Resin restorations had the lowest microleakage (0.58 ± 0.16 mm) and the lowest caries incidence. GIC exhibited results that were in between (0.72 ± 0.19). The groups differed significantly (p = 0.01 for caries severity and p = 0.002 for leakage). Conclusion: In comparison to Amalgam and GIC, Composite Resin demonstrated better marginal adaptation and resistance to secondary caries. These results highlight the significance of choosing restorative materials to reduce restoration failures.

Pakistan Journal of Medicine and DentistryVol. 15(1)
Northern Border University (SA), Karachi Medical and Dental College (PK), Isra University (PK), CMH Lahore Medical College and Institute of Dentistry (PK), Bahria University (PK)
Sustainable cities and communities
Openalex Percentile: Top 82%
Dental materials and restorations
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.