Loss of biomechanical features reveals smooth muscle disruption and disease progression in prostate cancer
This study establishes MRPX as a robust biomarker for prognostic stratification and therapeutic guidance in PCa, offering new insights into biomechanical regulation of tumor progression and providing a potential avenue for precision oncology.
Authors
- Yu Luo (ORCID: https://orcid.org/0000-0002-7335-020X)
- Wenjun Zhou (ORCID: https://orcid.org/0000-0002-7329-8149)
- Zixiong Jiang
- Shuai Su
- Zhangcheng Liu
- Liangdong Song
- Jindong Zhang
- Xiaoqi Deng
- Jue Wang
- Jingke He
- Chengcheng Wei
- Kun Han
- Yunfan Li
- Delin Wang
Institutions
- Army Medical University (CN)
- Xinqiao Hospital (CN)
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Panzhihua Central Hospital (CN)
- Zigong First People's Hospital (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Cancer Cell International
- Published
- 2026-01-20
- DOI
- https://doi.org/10.1186/s12935-026-04169-7
- Primary Topic
- Heat shock proteins research
- Type
- article
- Field-Weighted Citation Impact
- 0.00