Emerging minimally invasive laser and light-based therapies for glioblastoma: a systematic review
LITT and PDT are safe and effective adjunct therapies for glioblastoma patients, improving survival and reducing complications in selected patients. LITT mostly benefits patients with small, deep, or unresectable tumors, while PDT enhances outcomes when combined with gross total resection. Further large-scale trials are needed to optimize their use and refine patient selection.
Authors
- Billy McBenedict (ORCID: https://orcid.org/0000-0002-8987-5545)
- José Geraldo Medeiros Netto (ORCID: https://orcid.org/0009-0001-1040-6456)
- Lio Moreira
- Lucas Longo (ORCID: https://orcid.org/0000-0002-6180-8455)
- Rafaella Mafezoni
- Bruno Lima Pessôa
- Clara Peixoto Cirillo Costa
Institutions
- Universidade Federal Fluminense (BR)
- Hospital Universitário Antônio Pedro (BR)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2026-01-20
- DOI
- https://doi.org/10.3389/fonc.2025.1702399
- Primary Topic
- Photodynamic Therapy Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00