Phosphoglucose isomerase directs the inflammatory response, calcium influx and fibroblast migration in keloids

Our study is the first to show that PGI regulates the migration of KFs via a calcium influx-dependent inflammatory response and that blocking PGI might be a therapeutic strategy for keloids.

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Publication Details

Journal
Future Science OA
Published
2026-01-20
DOI
https://doi.org/10.1080/20565623.2026.2615968
Primary Topic
Dermatologic Treatments and Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Phosphoglucose isomerase directs the inflammatory response, calcium influx and fibroblast migration in keloids

Y. Lu, Wei‐Ting Wang, Chieh-Hsin Wu, Chun-Ching Lu
Future Science OA
Dermatologic Treatments and Research
article

Phosphoglucose isomerase directs the inflammatory response, calcium influx and fibroblast migration in keloids

Y. Lu, Wei‐Ting Wang, Chieh-Hsin Wu, Chun-Ching Lu
article en

Abstract

Our study is the first to show that PGI regulates the migration of KFs via a calcium influx-dependent inflammatory response and that blocking PGI might be a therapeutic strategy for keloids.

Future Science OAVol. 12(1)
Tri-Service General Hospital (TW), National Sun Yat-sen University (TW), National Yang Ming Chiao Tung University (TW), Kaohsiung Medical University (TW), Kaohsiung Medical University Chung-Ho Memorial Hospital (TW), Min-Hwei College of Health Care Management (TW), Kaohsiung Veterans General Hospital (TW), National Defense Medical Center (TW)
Openalex Percentile: Top 83%
Dermatologic Treatments and Research
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