Localized Choriocapillaris Flow Deficits at Perforating Vessel Sites in Myopic Eyes

Localized CCFDs were consistently observed at PSV sites in myopic eyes. Although higher age, global CCFD, and PSV area were associated with greater localized deficits, longer AXL was associated with lower CCFDs, possibly reflecting scleral remodeling or altered PSV orientation in more significant myopia. These findings highlight the relevance of PSVs as early modulators of CC flow before the development of pathologic myopia.

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Publication Details

Journal
Investigative Ophthalmology & Visual Science
Published
2026-01-20
DOI
https://doi.org/10.1167/iovs.67.1.43
Primary Topic
Ophthalmology and Visual Impairment Studies
Type
article
Field-Weighted Citation Impact
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article

Localized Choriocapillaris Flow Deficits at Perforating Vessel Sites in Myopic Eyes

Alberto Quarta, Alessandro Feo, F. Romano, Ceren Soylu et al.
Investigative Ophthalmology & Visual Science
Ophthalmology and Visual Impairment Studies
article

Localized Choriocapillaris Flow Deficits at Perforating Vessel Sites in Myopic Eyes

Alberto Quarta, Alessandro Feo, F. Romano, Ceren Soylu, Michele Reibaldi, Federico Corvi, Shinichiro Chujo, Rouzbeh Abbasgholizadeh, Chiara Olivieri, Enrico Borelli, Raiyna Rattu, Umberto Palumbo, Giulia Corradetti, Muneeswar G. Nittala, Srinivas R. Sadda, Marko Popovic, Mai Alhelaly, Giovanni Staurenghi
article en

Abstract

Localized CCFDs were consistently observed at PSV sites in myopic eyes. Although higher age, global CCFD, and PSV area were associated with greater localized deficits, longer AXL was associated with lower CCFDs, possibly reflecting scleral remodeling or altered PSV orientation in more significant myopia. These findings highlight the relevance of PSVs as early modulators of CC flow before the development of pathologic myopia.

Investigative Ophthalmology & Visual ScienceVol. 67(1)
University of California, Los Angeles (US), Mie University (JP), University of Toronto (CA), University of Milan (IT), Tanta University (EG), University of California System (US), University of Chieti-Pescara (IT), Luigi Sacco Hospital (IT), Doheny Eye Institute (US), Piedmont Reference Center for Epidemiology and Cancer Prevention (IT), University of Turin (IT)
Openalex Percentile: Top 83%
Ophthalmology and Visual Impairment Studies
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