Local Field Potentials in Movement Disorders: A Narrative Review
LFPs provide fundamental insights into disease-specific neural oscillations across PD, ET, dystonia, tics, and chorea. Pathological patterns serve as reliable biomarkers of symptom states. By leveraging these signals, DBS can be more accurately targeted, programming can be streamlined, and long-term outpatient monitoring can be enhanced. aDBS based on LFP biomarkers is already in clinical use for PD, offering superior motor control and fewer side effects than conventional stimulation.
Authors
- Gustavo da Cunha Ribas (ORCID: https://orcid.org/0000-0003-1997-0552)
- Renato P. Munhoz
- Nathalia C.B. Tortato
- Marina Farah
Institutions
- Pontifícia Universidade Católica do Paraná (BR)
- Toronto Western Hospital (CA)
- Hospital Universitário Cajuru (BR)
- Hospital Municipal São José (BR)
- Krembil Foundation (CA)
- Krembil Research Institute
Publication Details
- Journal
- Stereotactic and Functional Neurosurgery
- Published
- 2026-01-20
- DOI
- https://doi.org/10.1159/000550545
- Primary Topic
- Neurological disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00