Complete Pathological Response to Neoadjuvant Cisplatin, Etoposide, and Pembrolizumab in Small Cell Breast Carcinoma: A Case Report and Review of the Literature

This is the first reported case of SCBC successfully treated with neoadjuvant chemoimmunotherapy, achieving complete pathological remission. It highlights the potential role of ICIs in SCBC and supports future research into biomarker-driven strategies for this rare and aggressive.

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Publication Details

Journal
Case Reports in Oncology
Published
2026-01-20
DOI
https://doi.org/10.1159/000550080
Primary Topic
Lung Cancer Research Studies
Type
article
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article

Complete Pathological Response to Neoadjuvant Cisplatin, Etoposide, and Pembrolizumab in Small Cell Breast Carcinoma: A Case Report and Review of the Literature

Huei Ti Soh, Udit Nindra, Samriti Sood, Wei Chua et al.
Case Reports in Oncology
Lung Cancer Research Studies
article

Complete Pathological Response to Neoadjuvant Cisplatin, Etoposide, and Pembrolizumab in Small Cell Breast Carcinoma: A Case Report and Review of the Literature

Huei Ti Soh, Udit Nindra, Samriti Sood, Wei Chua, Kelly Mok, Frederick Ho
article en

Abstract

This is the first reported case of SCBC successfully treated with neoadjuvant chemoimmunotherapy, achieving complete pathological remission. It highlights the potential role of ICIs in SCBC and supports future research into biomarker-driven strategies for this rare and aggressive.

Case Reports in OncologyVol. 19(1)
Royal North Shore Hospital (AU), Liverpool Hospital (AU), Wollongong Hospital (AU), Shoalhaven District Memorial Hospital (AU)
Good health and well-being
Openalex Percentile: Top 83%
Lung Cancer Research Studies
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Complete Pathological Response to Neoadjuvant Cisplatin, Etoposide, and Pembrolizumab in Small Cell Breast Carcinoma: A Case Report and Review of the Literature — Huei Ti Soh, Udit Nindra, et al. · Case Reports in Oncology (2026) | TGRS Research Map | TGRS