Simulation Study on Parameter Optimization of Laser Acupuncture Based on a Human Acupoint Skin Model

To achieve precise and safe laser acupuncture treatment, a computational model of the skin acupoint was constructed utilizing COMSOL Multiphysics (Version 6.1). This model incorporates its multilayer anatomical structure: the epidermis, papillary dermis, reticular dermis, hypodermis, and muscle layer. A coupled multiphysics approach integrating geometric optics, radiation beams, and bioheat transfer was employed to investigate the effects of light source parameters and cooling layers on the photothermal response and thermal damage of acupoints. Under optimized parameters (808 nm, 3 mm beam waist, 50 mW) with a 0.5 mm glycerol layer, 600 s irradiation achieved a stable dermal temperature (40.86–42.04 °C) and a negligible epidermal thermal damage factor (0.0063), significantly below the subclinical injury threshold of 0.15; under identical parameters, the dermal temperature for the Gaussian periodic pulsed source was maintained between 38.85 and 40.35 °C, with a corresponding epidermal thermal damage factor of merely 0.0010. The model exhibited good robustness, tolerating variations of ±5% in laser power and ±40% in glycerol layer thickness. The resultant temperature deviations in the epidermis and dermis were well within the safe range, and the thermal damage factor remained below the injury threshold. This work serves as a guideline for selecting laser acupuncture parameters according to acupoint depth.