From Silence To Seizures: Benzodiazepine-Induced Neonatal Abstinence Syndrome In A Preterm Newborn– A Rare Case From Darul Sehat Hospital.

This case report delves into the clinical presentation, examination and management of a neonate from Pakistan, diagnosed with NEONATAL ABSTINENCE SYNDROME(NAS) at DarulSehat. It’s a withdrawal condition affecting infants with opioids or other Central Nervous System depressants exposure in utero. The subject, born at 33 weeks via emergency C-section to a mother with history of opioid use exhibited classical symptoms of NAS including high pitched cry, hyperirritability, seizures, tachypnea, tremors-within 24 hours postpartum. Thorough clinical evaluation supported by laboratory and imaging findings led to diagnosis of NAS secondary to maternal benzodiazepine abuse during pregnancy. A Finnegan Neonatal Abstinence Scoring System was used to monitor the severity of withdrawal symptoms and guide treatment. This case accentuates importance of early identification, standardized assessment protocols and multidisciplinary approach of NAS to improve short and long term outcomes. It also emphasizes the ongoing need for support systems for families affected by this disorder.

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Publication Details

Journal
Pakistan Journal of Medicine and Dentistry
Published
2026-01-14
DOI
https://doi.org/10.36283/ziun-pjmd15-1/032
Primary Topic
Prenatal Substance Exposure Effects
Type
article
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article

From Silence To Seizures: Benzodiazepine-Induced Neonatal Abstinence Syndrome In A Preterm Newborn– A Rare Case From Darul Sehat Hospital.

Sidra Tul Muntaha, Saba Fareed, Taiba, Alisha et al.
Pakistan Journal of Medicine and Dentistry
Prenatal Substance Exposure Effects
article

From Silence To Seizures: Benzodiazepine-Induced Neonatal Abstinence Syndrome In A Preterm Newborn– A Rare Case From Darul Sehat Hospital.

Sidra Tul Muntaha, Saba Fareed, Taiba, Alisha, Amna, Ayesha, Ayesha Khatoon
article en

Abstract

This case report delves into the clinical presentation, examination and management of a neonate from Pakistan, diagnosed with NEONATAL ABSTINENCE SYNDROME(NAS) at DarulSehat. It’s a withdrawal condition affecting infants with opioids or other Central Nervous System depressants exposure in utero. The subject, born at 33 weeks via emergency C-section to a mother with history of opioid use exhibited classical symptoms of NAS including high pitched cry, hyperirritability, seizures, tachypnea, tremors-within 24 hours postpartum. Thorough clinical evaluation supported by laboratory and imaging findings led to diagnosis of NAS secondary to maternal benzodiazepine abuse during pregnancy. A Finnegan Neonatal Abstinence Scoring System was used to monitor the severity of withdrawal symptoms and guide treatment. This case accentuates importance of early identification, standardized assessment protocols and multidisciplinary approach of NAS to improve short and long term outcomes. It also emphasizes the ongoing need for support systems for families affected by this disorder.

Pakistan Journal of Medicine and DentistryVol. 15(1)
Liaquat National Hospital (PK)
Good health and well-being
Openalex Percentile: Top 84%
Prenatal Substance Exposure Effects
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From Silence To Seizures: Benzodiazepine-Induced Neonatal Abstinence Syndrome In A Preterm Newborn– A Rare Case From Darul Sehat Hospital. — Sidra Tul Muntaha, Saba Fareed, et al. · Pakistan Journal of Medicine and Dentistry (2026) | TGRS Research Map | TGRS