Rapid diagnostic value of next-generation sequencing-based technologies in childhood pneumonia

NGS is a promising tool for rapid and accurate etiologic diagnosis of pneumonia in children. The combination of NGS with albumin levels may serve as an effective screening strategy, potentially enhancing clinical management through earlier intervention and targeted therapy. Further validation in larger cohorts is warranted to establish the clinical utility of this approach.

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Publication Details

Journal
Frontiers in Pediatrics
Published
2026-01-20
DOI
https://doi.org/10.3389/fped.2025.1662367
Primary Topic
Pneumonia and Respiratory Infections
Type
article
Field-Weighted Citation Impact
0.00
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article

Rapid diagnostic value of next-generation sequencing-based technologies in childhood pneumonia

Kaihui Ma, Yanfei Chen, Xiaoli Zhu, Hongxia Liu et al.
Frontiers in Pediatrics
Pneumonia and Respiratory Infections
article

Rapid diagnostic value of next-generation sequencing-based technologies in childhood pneumonia

Kaihui Ma, Yanfei Chen, Xiaoli Zhu, Hongxia Liu, Yanli Zhang, Fang Fang
article en

Abstract

NGS is a promising tool for rapid and accurate etiologic diagnosis of pneumonia in children. The combination of NGS with albumin levels may serve as an effective screening strategy, potentially enhancing clinical management through earlier intervention and targeted therapy. Further validation in larger cohorts is warranted to establish the clinical utility of this approach.

Frontiers in PediatricsVol. 13
Nantong University (CN), The Affiliated Taizhou People's Hospital of Nanjing Medical University (CN), Yancheng Second People's Hospital (CN), Changzhou No.2 People's Hospital (CN)
Openalex Percentile: Top 83%
Pneumonia and Respiratory Infections
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