Efficacy and Safety of Ligelizumab in Individuals With Confirmed Peanut Allergy

Ligelizumab 240 mg demonstrated clinical superiority over placebo, with favourable tolerability, in treating IgE-mediated peanut allergy, despite early termination of the study.

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Publication Details

Journal
Allergy
Published
2026-01-20
DOI
https://doi.org/10.1111/all.70206
Primary Topic
Food Allergy and Anaphylaxis Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Efficacy and Safety of Ligelizumab in Individuals With Confirmed Peanut Allergy

Jeffrey Leflein, Kirsten P. Perrett, Benjamin Ortiz, Aurélie Gautier et al.
Allergy
Food Allergy and Anaphylaxis Research
article

Efficacy and Safety of Ligelizumab in Individuals With Confirmed Peanut Allergy

Jeffrey Leflein, Kirsten P. Perrett, Benjamin Ortiz, Aurélie Gautier, Kari Christine Nadeau, Joseph L. Roberts, A. Muraro, Motoi Hosoe, Rima A Rachid, Wei Qiang Wang, Philippe Bégin, Iván Bottoli, Gideon Lack, Matthew Greenhawt, Motohiro Ebisawa, Munir Winkel, Aikaterini Anagnostou, Eva Schlosser
article en

Abstract

Ligelizumab 240 mg demonstrated clinical superiority over placebo, with favourable tolerability, in treating IgE-mediated peanut allergy, despite early termination of the study.

Allergy
Novartis (Switzerland) (CH), Boston Children's Hospital (US), Royal Children's Hospital (AU), Harvard University (US), University of Padua (IT), Emory University (US), Asthma and Allergy Foundation of America (US), Centre Hospitalier Universitaire Sainte-Justine (CA), Novartis (China) (CN), National Sagamihara Hospital (JP), Ann Arbor Center for Independent Living (US), Texas Children's Hospital (US), Novartis Institutes for BioMedical Research, London School of Economics and Political Science (GB)
AstraZeneca, Sanofi, Food Allergy Research and Education, Regeneron Pharmaceuticals, Immune Tolerance Network, Aimmune Therapeutics, Allergy Therapeutics, Federal Agency for Science and Innovation, National Institutes of Health, Genentech, Novartis Pharma, Medical Research Council, National Health and Medical Research Council, National Heart, Lung, and Blood Institute, National Institute of Allergy and Infectious Diseases, National Institute of Environmental Health Sciences
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Openalex Percentile: Top 87%
Food Allergy and Anaphylaxis Research
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