Efficacy and Safety of Ligelizumab in Individuals With Confirmed Peanut Allergy
Ligelizumab 240 mg demonstrated clinical superiority over placebo, with favourable tolerability, in treating IgE-mediated peanut allergy, despite early termination of the study.
Authors
- Jeffrey Leflein
- Kirsten P. Perrett (ORCID: https://orcid.org/0000-0002-5683-996X)
- Benjamin Ortiz (ORCID: https://orcid.org/0000-0001-6950-5582)
- Aurélie Gautier
- Kari Christine Nadeau (ORCID: https://orcid.org/0000-0002-2146-2955)
- Joseph L. Roberts (ORCID: https://orcid.org/0000-0001-6839-1173)
- A. Muraro
- Motoi Hosoe (ORCID: https://orcid.org/0000-0001-6848-3713)
- Rima A Rachid
- Wei Qiang Wang (ORCID: https://orcid.org/0000-0002-1430-1360)
- Philippe Bégin
- Iván Bottoli
- Gideon Lack
- Matthew Greenhawt
- Motohiro Ebisawa
- Munir Winkel
- Aikaterini Anagnostou
- Eva Schlosser
Institutions
- Novartis (Switzerland) (CH)
- Boston Children's Hospital (US)
- Royal Children's Hospital (AU)
- Harvard University (US)
- University of Padua (IT)
- Emory University (US)
- Asthma and Allergy Foundation of America (US)
- Centre Hospitalier Universitaire Sainte-Justine (CA)
- Novartis (China) (CN)
- National Sagamihara Hospital (JP)
- Ann Arbor Center for Independent Living (US)
- Texas Children's Hospital (US)
- Novartis Institutes for BioMedical Research
- London School of Economics and Political Science (GB)
Publication Details
- Journal
- Allergy
- Published
- 2026-01-20
- DOI
- https://doi.org/10.1111/all.70206
- Primary Topic
- Food Allergy and Anaphylaxis Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- AstraZeneca
- Sanofi
- Food Allergy Research and Education
- Regeneron Pharmaceuticals
- Immune Tolerance Network
- Aimmune Therapeutics
- Allergy Therapeutics
- Federal Agency for Science and Innovation
- National Institutes of Health
- Genentech
- Novartis Pharma
- Medical Research Council
- National Health and Medical Research Council
- National Heart, Lung, and Blood Institute
- National Institute of Allergy and Infectious Diseases
- National Institute of Environmental Health Sciences