A telomere-based prognostic model incorporating E2F1, MYCN, VPS72, CFAP53, OR8A1, and TXNRD1 for hepatocellular carcinoma

This study established a telomere-based prognostic model for HCC. This model provides reliable survival prediction, captures key tumor microenvironment features, and yields insights to support personalized therapeutic strategies, offering a valuable tool for clinical decision-making in HCC.

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Publication Details

Journal
European journal of medical research
Published
2026-01-20
DOI
https://doi.org/10.1186/s40001-026-03900-4
Primary Topic
Telomeres, Telomerase, and Senescence
Type
article
Field-Weighted Citation Impact
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article

A telomere-based prognostic model incorporating E2F1, MYCN, VPS72, CFAP53, OR8A1, and TXNRD1 for hepatocellular carcinoma

Weizheng Wang, Jiachun Sun, Leiya Fu, Xinyu Gu et al.
European journal of medical research
Telomeres, Telomerase, and Senescence
article

A telomere-based prognostic model incorporating E2F1, MYCN, VPS72, CFAP53, OR8A1, and TXNRD1 for hepatocellular carcinoma

Weizheng Wang, Jiachun Sun, Leiya Fu, Xinyu Gu, Yafei Wang, Zihan Yang
article en

Abstract

This study established a telomere-based prognostic model for HCC. This model provides reliable survival prediction, captures key tumor microenvironment features, and yields insights to support personalized therapeutic strategies, offering a valuable tool for clinical decision-making in HCC.

European journal of medical researchVol. 31(1)
Henan University of Science and Technology (CN), First Affiliated Hospital of Henan University of Science and Technology (CN), First Affiliated Hospital of Zhengzhou University (CN)
Peace, Justice and strong institutions
Openalex Percentile: Top 84%
Telomeres, Telomerase, and Senescence
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