Effects of a Novel Dexamethasone Hydrogel Drug Delivery System on Cytokine and Mucin Expression in a Three-Dimensional In Vitro Conjunctival Inflammation Model

We established an inflammation model, in which the effects of novel treatment options on cytokine and mucin expression can be analyzed. This opens a new in vitro test platform for DED medication and enables deeper investigations into conjunctival mucin expression in inflamed tissue.

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Publication Details

Journal
Investigative Ophthalmology & Visual Science
Published
2026-01-20
DOI
https://doi.org/10.1167/iovs.67.1.42
Primary Topic
Ocular Surface and Contact Lens
Type
article
Field-Weighted Citation Impact
0.00
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article

Effects of a Novel Dexamethasone Hydrogel Drug Delivery System on Cytokine and Mucin Expression in a Three-Dimensional In Vitro Conjunctival Inflammation Model

Daniel Kampik, Malik Salman Haider, Jost Hillenkamp, Christian Lotz et al.
Investigative Ophthalmology & Visual Science
Ocular Surface and Contact Lens
article

Effects of a Novel Dexamethasone Hydrogel Drug Delivery System on Cytokine and Mucin Expression in a Three-Dimensional In Vitro Conjunctival Inflammation Model

Daniel Kampik, Malik Salman Haider, Jost Hillenkamp, Christian Lotz, Raoul Verma-Fuehring, Julian Schwebler, Constantin Berger, Niloofar Kalantari
article en

Abstract

We established an inflammation model, in which the effects of novel treatment options on cytokine and mucin expression can be analyzed. This opens a new in vitro test platform for DED medication and enables deeper investigations into conjunctival mucin expression in inflamed tissue.

Investigative Ophthalmology & Visual ScienceVol. 67(1)
Universitätsklinikum Würzburg (DE), Fraunhofer Institute for Silicate Research (DE)
Good health and well-being
Openalex Percentile: Top 84%
Ocular Surface and Contact Lens
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