Extracellular vesicles derived from human amniotic fluid stem cells improve bladder dysfunction in rat model of diabetic atherosclerosis
hAFSC-EVs treatment can help restore DMA-induced bladder dysfunction, which is associated with lowered blood glucose levels, reduced arterial wall thickness, and decreased TNF-α, IL-6, TGF-β1, Smad3, and CTGF expression.
Authors
- Aileen Ro
- Chu-Ya Liang
- Steven W Shaw
- Yi-Hao Lin
- Ching-Chung Liang
- Yung-Hsin Huang
Institutions
- Chang Gung University of Science and Technology (TW)
- Chang Gung University (TW)
- Chang Gung Memorial Hospital (TW)
- Linkou Chang Gung Memorial Hospital (TW)
- University College London (GB)
Publication Details
- Journal
- World Journal of Stem Cells
- Published
- 2026-01-20
- DOI
- https://doi.org/10.4252/wjsc.v18.i1.113614
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00