Mitoregulin supports mitochondrial membrane integrity and protects against cardiac ischaemia–reperfusion injury
Our work supports a model in which Mtln binds cardiolipin and stabilizes mitochondrial membranes to broadly influence diverse mitochondrial functions, including lipid metabolism, while also protecting against stress.
Authors
- Colleen S. Stein (ORCID: https://orcid.org/0000-0002-7676-6278)
- X Zhang
- Nathan H. Witmer (ORCID: https://orcid.org/0000-0002-0369-0305)
- Adam C. Straub (ORCID: https://orcid.org/0000-0003-0542-9466)
- Scott Hahn
- Ryan L Boudreau
- Edward Ross Pennington
- Saame Raza Shaikh
Institutions
- University of North Carolina at Chapel Hill (US)
- University of Iowa (US)
- University of Pittsburgh (US)
- Department of Health (ZA)
Publication Details
- Journal
- Cardiovascular Research
- Published
- 2026-01-15
- DOI
- https://doi.org/10.1093/cvr/cvag011
- Primary Topic
- Mitochondrial Function and Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00