Ectopic endometrial mesenchymal stem cell-derived exosomal miR-4466 promotes angiogenesis by targeting RUNX1 in adenomyosis
Our study demonstrates that exosomal miR-4466 derived from ectopic eMSCs promotes angiogenesis by targeting the RUNX1/VEGFA axis in AM. These findings may offer new insights into therapeutic targets and treatment strategies for the anti-angiogenic treatment of AM.
Authors
- Tao Gui (ORCID: https://orcid.org/0000-0003-4764-4834)
- Meihua Huang
- Jiali Sun
- Xinjun Wei
- Yingying Qiu
- Bei Wang
- Jindan Wang
- Yongyan Ni
- Zhenli Li
Institutions
- Nanjing University of Chinese Medicine (CN)
- Xuzhou Medical College (CN)
- Affiliated Hospital of Xuzhou Medical College (CN)
Publication Details
- Journal
- Biochemistry and Biophysics Reports
- Published
- 2026-01-20
- DOI
- https://doi.org/10.1016/j.bbrep.2026.102457
- Primary Topic
- Endometriosis Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00