CD276 immature glycosylation drives colorectal cancer aggressiveness and T cell mediated immune escape
Immature CD276 glycosylation promotes CRC aggressiveness and immune escape, representing a candidate prognostic biomarker and therapeutic target.
Authors
- Lúcio Lara Santos (ORCID: https://orcid.org/0000-0002-0521-5655)
- André M. N. Silva (ORCID: https://orcid.org/0000-0001-5554-7714)
- Sofia Cotton (ORCID: https://orcid.org/0000-0002-8112-5619)
- Francisco Amado (ORCID: https://orcid.org/0000-0001-8256-1749)
- Marta Relvas‐Santos (ORCID: https://orcid.org/0000-0001-5764-5414)
- José Alexandre Ferreira (ORCID: https://orcid.org/0000-0002-0097-6148)
- Martina Spohr Gonçalves
- Andreia Brandão (ORCID: https://orcid.org/0000-0003-0938-1543)
- Rui Freitas
- Andreia Peixoto
- Dylan Ferreira
- Beatriz Marinho-Santos
- Andreia Miranda
- Eduardo Ferreira
- Mariana Magalhães
- Carlos Palmeira
- Paula Paulo
- Janine Soares
- Luís Pedro Afonso
Institutions
- Fernando Pessoa University (PT)
- Universidade do Porto (PT)
- Instituto Português de Oncologia Francisco Gentil (PT)
- Rede de Química e Tecnologia (PT)
- i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto (PT)
- University of Aveiro (PT)
- Polytechnic Institute of Porto (PT)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2026-01-20
- DOI
- https://doi.org/10.1186/s12964-026-02672-y
- Primary Topic
- Glycosylation and Glycoproteins Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00