Oxyphenbutazone improves memory and learning impairments in LPS-induced neurotoxicity via modulating TGF-β/NF-κB/IκB-α pathways: In silico and in vivo study
These findings suggest the therapeutic potential of OPB in mitigating neurotoxicity and the associated cognitive disabilities.
Authors
- Sattam Khulaif Alenezi (ORCID: https://orcid.org/0000-0002-4988-9838)
- Imran Kazmi (ORCID: https://orcid.org/0000-0003-1881-5219)
- Faisal Imam
- Muhammad Afzal
- Tariq G. Alsahli
- Reem ALQahtani
- Khalid Saad Alharbi
Institutions
- Princess Nourah bint Abdulrahman University (SA)
- Qassim University (SA)
- King Abdulaziz University (SA)
- Jouf University (SA)
- King Saud University (SA)
- Batterjee Medical College
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-01-20
- DOI
- https://doi.org/10.1371/journal.pone.0337611
- Primary Topic
- NF-κB Signaling Pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Qassim University