Hypnotic doses of fazamorexant induced less impairment on balance and cognition than zolpidem in healthy younger and elderly individualse
Clinically hypnotic doses of fazamorexant induced less balance, judgement and memory impairment in healthy adults and elderly volunteers compared to the comprehensive suppression of zolpidem on the neurological system. These preliminary results suggest that fazamorexant is a potentially safer drug for insomnia. No age-related pharmacokinetic difference was identified with fazamorexant.
Authors
- Wang Ruwei
- Chen Xia
- Jin Lü
- Huang Xingxing
Institutions
- Beijing Tian Tan Hospital (CN)
- Yangtze River Pharmaceutical Group (China) (CN)
- Hangzhou DAC Biotech (China) (CN)
Publication Details
- Journal
- British Journal of Clinical Pharmacology
- Published
- 2026-01-19
- DOI
- https://doi.org/10.1002/bcp.70414
- Primary Topic
- Sleep and Wakefulness Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00