Progressive exacerbation of neurological symptoms in a patient with neurosyphilis following T9-T10 intradural space-occupying lesion resection: a case report
This case emphasizes the importance of preoperative syphilis antibody screening, especially in elderly patients with a history of syphilis. The immunosuppressed state may contribute to the reactivation of syphilis spirochetes; therefore, it is important to consider this potential risk and take appropriate precautions when performing surgical treatments such as spinal surgery. Penicillin remains the therapeutic agent of choice for neurosyphilis, and early diagnosis and treatment are critical to the patient's prognosis.
Authors
- Ying Meng (ORCID: https://orcid.org/0000-0001-7169-8037)
- Yan Bo
- Hongtao Wei
Institutions
- Minzu University of China (CN)
- The Neurological Institute (US)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-01-20
- DOI
- https://doi.org/10.3389/fimmu.2026.1729673
- Primary Topic
- Syphilis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00