Use of biomarkers in the early diagnosis of Ischemic Stroke: A Systematic Review

Blood-based biomarkers, especially when used in multi-marker panels, demonstrate considerable potential as triage tools for early AIS diagnosis. Their application in point-of-care settings could reduce diagnostic uncertainty and accelerate time to treatment. However, prospective validation in real-world emergency environments is essential prior to clinical implementation.

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Publication Details

Journal
Clinical and Experimental Emergency Medicine
Published
2026-01-14
DOI
https://doi.org/10.15441/ceem.25.167
Primary Topic
Acute Ischemic Stroke Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Use of biomarkers in the early diagnosis of Ischemic Stroke: A Systematic Review

Jeffrey Penny, Rosa Castillo-Olate, José-Manuel León
Clinical and Experimental Emergency Medicine
Acute Ischemic Stroke Management
article

Use of biomarkers in the early diagnosis of Ischemic Stroke: A Systematic Review

Jeffrey Penny, Rosa Castillo-Olate, José-Manuel León
article en

Abstract

Blood-based biomarkers, especially when used in multi-marker panels, demonstrate considerable potential as triage tools for early AIS diagnosis. Their application in point-of-care settings could reduce diagnostic uncertainty and accelerate time to treatment. However, prospective validation in real-world emergency environments is essential prior to clinical implementation.

Clinical and Experimental Emergency Medicine
University of Bío-Bío (CL), Manchester Academic Health Science Centre (GB), University of Manchester (GB), University of Chile (CL)
Good health and well-being
Openalex Percentile: Top 83%
Acute Ischemic Stroke Management
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