A Primer for Pediatric Plastic Surgeons on Pediatric Head and Neck Malignancies

Pediatric head and neck malignancies are rare; however, their incidence is rising rapidly, with an incidence of 3.29 diagnoses per 100,000 person-years. These malignancies often present with nonspecific symptoms distinct from adults, making early diagnosis more challenging. Recognizing early symptoms in children is essential to improve treatment and long-term outcomes. This review discusses the incidence, pathogenesis, classification, and presentation of the common pediatric head and neck malignancies, including lymphoma, soft tissue sarcoma, thyroid carcinoma, salivary gland malignancies, bone malignancies, nasopharyngeal carcinoma, and melanoma.

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Publication Details

Journal
Annals of Plastic Surgery
Published
2026-01-19
DOI
https://doi.org/10.1097/sap.0000000000004604
Primary Topic
Head and Neck Cancer Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

A Primer for Pediatric Plastic Surgeons on Pediatric Head and Neck Malignancies

Daniel Najafali, Roberto L. Flores, Joseph Lopez, Benjamin Oakes et al.
Annals of Plastic Surgery
Head and Neck Cancer Studies
article

A Primer for Pediatric Plastic Surgeons on Pediatric Head and Neck Malignancies

Daniel Najafali, Roberto L. Flores, Joseph Lopez, Benjamin Oakes, Michael Pozin, Simo Kraguljac, Jordan Whittles, Jason W. Yu, Fouad Hajjar, Hana Seif, Muhammad Seif
article en

Abstract

Pediatric head and neck malignancies are rare; however, their incidence is rising rapidly, with an incidence of 3.29 diagnoses per 100,000 person-years. These malignancies often present with nonspecific symptoms distinct from adults, making early diagnosis more challenging. Recognizing early symptoms in children is essential to improve treatment and long-term outcomes. This review discusses the incidence, pathogenesis, classification, and presentation of the common pediatric head and neck malignancies, including lymphoma, soft tissue sarcoma, thyroid carcinoma, salivary gland malignancies, bone malignancies, nasopharyngeal carcinoma, and melanoma.

Annals of Plastic Surgery
University of Central Florida (US), Texas Christian University (US), University of Illinois Urbana-Champaign (US), Illinois College (US), University of South Florida (US), Loma Linda University (US), NYU Langone Health (US), Children's Hospital Colorado (US), Schlumberger (Ireland) (IE), AdventHealth for Children (US), University of Colorado Denver (US), Florida College (US)
Good health and well-being
Openalex Percentile: Top 83%
Head and Neck Cancer Studies
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A Primer for Pediatric Plastic Surgeons on Pediatric Head and Neck Malignancies — Daniel Najafali, Roberto L. Flores, et al. · Annals of Plastic Surgery (2026) | TGRS Research Map | TGRS