Blood Urea Nitrogen‐to‐Creatinine Ratio to Differentiate Upper From Lower Gastrointestinal Bleeding: A Systematic Review and Meta‐Analysis
BUN/Cr demonstrates moderate diagnostic accuracy for distinguishing UGIB from LGIB, particularly at a threshold of ≥ 22. This readily accessible and inexpensive blood test may assist in early clinical triage and assessment of the location of GI bleeding, particularly in those patients where the clinical presentation is obscure.
Authors
- Pojsakorn Danpanichkul (ORCID: https://orcid.org/0000-0002-9121-165X)
- Ramesh Lamichhane (ORCID: https://orcid.org/0000-0003-4559-7261)
- Thai Hau Koo (ORCID: https://orcid.org/0009-0003-6671-0929)
- Murlidhar Murlidhar
- Richard C. K. Wong
- Daniel Martin Simadibrata
- Derren David Christian Homenta Rampengan
Institutions
- Texas Tech University (US)
- Mayo Clinic (US)
- WinnMed (US)
- Hospital Universiti Sains Malaysia (MY)
- Mayo Clinic in Arizona (US)
- MetroHealth Medical Center (US)
- Sam Ratulangi University (ID)
- Case Western Reserve University (US)
- Texas Tech University Health Sciences Center (US)
Publication Details
- Journal
- Journal of Gastroenterology and Hepatology
- Published
- 2026-01-19
- DOI
- https://doi.org/10.1111/jgh.70224
- Primary Topic
- Gastrointestinal Bleeding Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00