Expression of Calcitonin Gene-related Peptide and Its Application to Cochlear Implantation Under Local Anesthesia With Monitored Anesthesia Care in the Very Elderly: The University of California, Los Angeles, Experience

CGRP is a valuable marker for identifying pain-sensitive regions in the temporal bone relevant to CI. Histopathology-guided refinements in local anesthesia enhance intraoperative comfort and feasibility of CI under MAC in the very elderly with the potential to improve postoperative outcomes and broaden candidacy for this population.

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Publication Details

Journal
Otology & Neurotology
Published
2026-01-20
DOI
https://doi.org/10.1097/mao.0000000000004810
Primary Topic
Anesthesia and Neurotoxicity Research
Type
article
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article

Expression of Calcitonin Gene-related Peptide and Its Application to Cochlear Implantation Under Local Anesthesia With Monitored Anesthesia Care in the Very Elderly: The University of California, Los Angeles, Experience

Adam Y. Xiao, Gail Ishiyama, Christine T. Trieu, Iván A. López et al.
Otology & Neurotology
Anesthesia and Neurotoxicity Research
article

Expression of Calcitonin Gene-related Peptide and Its Application to Cochlear Implantation Under Local Anesthesia With Monitored Anesthesia Care in the Very Elderly: The University of California, Los Angeles, Experience

Adam Y. Xiao, Gail Ishiyama, Christine T. Trieu, Iván A. López, Michelle L. Harvey, Linda Li, Qianjie Fu, Akira Ishiyama
article en

Abstract

CGRP is a valuable marker for identifying pain-sensitive regions in the temporal bone relevant to CI. Histopathology-guided refinements in local anesthesia enhance intraoperative comfort and feasibility of CI under MAC in the very elderly with the potential to improve postoperative outcomes and broaden candidacy for this population.

Otology & NeurotologyVol. 47(4)
University of California, Los Angeles (US)
Good health and well-being
Openalex Percentile: Top 88%
Anesthesia and Neurotoxicity Research
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Expression of Calcitonin Gene-related Peptide and Its Application to Cochlear Implantation Under Local Anesthesia With Monitored Anesthesia Care in the Very Elderly: The University of California, Los Angeles, Experience — Adam Y. Xiao, Gail Ishiyama, et al. · Otology & Neurotology (2026) | TGRS Research Map | TGRS