Maresin 1 ameliorates myocardial ischaemia‒reperfusion injury by promoting tissue resident macrophage efferocytosis

Our findings prove that MaR1 plays a protective role in myocardial I/R injury by facilitating efferocytosis by RMs and the resolution of inflammation. These results offer novel therapeutic perspectives for the management of myocardial I/R injury.

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Publication Details

Journal
Cardiovascular Research
Published
2026-01-15
DOI
https://doi.org/10.1093/cvr/cvag017
Primary Topic
Phagocytosis and Immune Regulation
Type
article
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0.00
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article

Maresin 1 ameliorates myocardial ischaemia‒reperfusion injury by promoting tissue resident macrophage efferocytosis

Xuan Sun, Yawei Zhao, Anning Du, Bin Xu et al.
Cardiovascular Research
Phagocytosis and Immune Regulation
article

Maresin 1 ameliorates myocardial ischaemia‒reperfusion injury by promoting tissue resident macrophage efferocytosis

Xuan Sun, Yawei Zhao, Anning Du, Bin Xu, Zhang Ye, Yue Cai, Yuting Feng, Zhonghai Wei, Zhenzhu Cao
article en

Abstract

Our findings prove that MaR1 plays a protective role in myocardial I/R injury by facilitating efferocytosis by RMs and the resolution of inflammation. These results offer novel therapeutic perspectives for the management of myocardial I/R injury.

Cardiovascular ResearchVol. 122(3)
Tongren Hospital (CN), Nanjing Drum Tower Hospital (CN)
Good health and well-being
Openalex Percentile: Top 83%
Phagocytosis and Immune Regulation
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Maresin 1 ameliorates myocardial ischaemia‒reperfusion injury by promoting tissue resident macrophage efferocytosis — Xuan Sun, Yawei Zhao, et al. · Cardiovascular Research (2026) | TGRS Research Map | TGRS