Parental Age and Childhood Allergy Risk
In this cohort study of 34 942 mother-child pairs, children of older mothers had reduced odds of food allergy, wheezing, and HDM sensitization in early childhood, suggesting that advanced maternal age may be protective against the development of allergic diseases in early childhood.
Authors
- Tomoki Nishizawa
- Minaho Nishizato (ORCID: https://orcid.org/0000-0002-1248-2807)
- Natsuhiko Kumasaka (ORCID: https://orcid.org/0000-0002-3557-0375)
- 上島 通浩
- Kyongsun Pak (ORCID: https://orcid.org/0000-0002-0934-8949)
- Shintaro Iwamoto (ORCID: https://orcid.org/0000-0001-9266-7811)
- Yasuhiro Takeshima (ORCID: https://orcid.org/0000-0002-6468-7185)
- Limin Yang (ORCID: https://orcid.org/0000-0002-2173-4439)
- Kei Sakamoto (ORCID: https://orcid.org/0000-0002-3632-5777)
- Yukihiro Ohya
- Chisato Mori
- Seiji Kageyama
- Miori Sato
- Japan Environment and Children’s Study (JECS) Group
- Kari C. Nadeau
- Shoichi Ohga
- Ryoji Shinohara
- Chiharu Ota
- Shuichi Ito
- Kiwako Yamamoto-Hanada
- Ryo Kawasaki
- Hidekuni Inadera
- Daisuke Harama
- Narufumi Suganuma
- Reiko Kishi
- Koichi Hashimoto
- Takeo Nakayama
- Shin Yamazaki
Institutions
- Harvard University (US)
- Fujita Health University (JP)
- Nagoya City University (JP)
- National Center For Child Health and Development (JP)
- Children's Center (US)
- Institute of Science Tokyo (JP)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2026-01-20
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.54694
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00